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£70.00
£70.00
ISBN: 978-0-521-51778-2
Page count: 271
Publisher: Cambridge UP
Publication year: 2010
Protecting the reproductive potential of young patients undergoing cancer therapy is increasingly important. With modern treatment protocols, 80% of patients can be expected to survive. It has been estimated that up to one in 250 young adults will be a survivor of childhood cancer in the future; infertility, however, may be a consequence.
A wide range of fertility preservation methods may be to these patients before treatment is started, Including embryo, gamete, and gonadal tissue cryopreservation, and oophoropexy. As such fertility preservation methods are increasingly being offered by clinicians, this systematic and comprehensive textbook dealing with the cryobiology, technology and clinical approach to this therapy will be essential reading for infertility specialists, embryologists, oncologists, cryobiologists, ObGyns, andrologists, and urologists with an interest in fertility preservation.
Fertility Cryopreservation reviews all the techniques of this increasingly important field within reproductive medicine. It covers the basic principles of pertinent cryobiology, and contains major sections on the different therapies available, written by international specialists combining experience from both academic centers and commercial industries.
Table of contents:
Part I. Cryobiology:
1. Cryobiology: an overview
2. Suppression of ice in aqueous solutions and its application to vitrification in an ART setting
3. Pathway for the movement of water and cryoprotectants in mouse oocytes and embryos at different stages - its relevance to cryopreservation
4. Cryoprotectants
Part II. Cryopreservation of Sperm and Testicular Tissue:
5. Cryopreservation of sperm: an overview
6. Sperm cryopreservation for donor program
7. Cryopreservation of surgically retrieved sperm
8. Testicular tissue cryopreservation
Part III. Cryopreservation of Embryos:
9. Cryopreservation of embryos: an overview
10. Cryopreservation of pronuclear stage human embryos
11. Cryopreservation of day two and day three embryos
12. Cryopreservation of blastocysts
13. Aseptic vitrification of human blastocysts: protocol development and clinical application
Part IV. Cryopreservation of Oocytes:
14. Cryopreservation of human oocytes: an overview
15. Cryopreservation of oocytes by slow cooling
16. Vitrification of human oocytes with different tools
17. Vitrification of human oocytes using the McGill Cryoleaf
18. Cryopreservation of human oocytes and embryos by direct plunging into liquid nitrogen and its aseptic approach
19. Vitrification of human oocytes for a donor program
20. Obstetric and perinatal outcomes in pregnancies conceived following oocyte cryopreservation
Part V. Cryopreservation of Ovarian Tissue:
21. Cryopreservation of ovarian tissue: an overview
22. In vitro culture of human primordial follicles
23. Cryobanking of human ovarian tissue: concept of formation and perspectives of development
24. Transplantation of cryopreserved ovarian tissues
25. Whole ovary cryopreservation
26. Transplantation of whole frozen-thawed ovaries
27. Ethical considerations in fertility cryopreservation in young cancer patients
