Introduction to ovulatory dysfunction

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Mature Graafian follicle

Ovulation is a complex process that requires a functioning hypothalamo-pituitary-ovarian axis, responsive target organs and inter-related feedback mechanisms.

Ovulatory dysfunction is a group of disorders with variable clinical presentations, and that occasionally have serious long-term adverse effects. Anovulation, oligo-ovulation and amenorrhoea are ovulatory disorders that account for 30% of female fertility problems.

This tutorial reviews ovulatory dysfunction and its management. It aims to improve your basic knowledge and understanding of the complex endocrinal and physiological changes of ovulation. It will also enhance your ability to assess and appropriately manage the causes of anovulation.

Learning objectives

When you have completed this tutorial you will:

  • be able to understand the physiology of ovulation
  • have the basic knowledge of the pathophysiology and clinical presentations of ovulatory dysfunction
  • be able to classify ovulatory disorders on the basis of their anatomical levels
  • be able to choose the appropriate treatment and understand the principles of management, including reduction of complications such as ovarian hyperstimulation and multiple pregnancy

Last updated:28/03/11 (Section on Turner syndrome and related assessments updated by Mr Rashmi Patel)

17/05/10 (tutorial reviewed and updated by Mr Rashmi Patel)

14/11/08 (news article added in PCOS management)


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