Endometrial cancer follow-up - query bank

Question: What is the evidence based follow up protocol for a 50 year old woman treated for endometrial cancer?

Please note: the search for this response was carried out over 1 year ago. Eligible users may request an update of the evidence by submitting a new Clinical Query here.

Answer: Three guidelines include recommendations for follow up based on the opinion of experts, in the absence of any RCTs:

  1. Endometrial carcinoma: ESMO clinical recommendations for diagnosis, treatment and follow-up. Baekelandt MM, Castiglione M; European Society for Medical Oncology Guidelines Working Group. Ann Oncol. 2009 May;20 Suppl 4:29-31.
  2. Interdisciplinary S2k guidelines on the diagnosis and treatment of endometrial carcinoma. Emons G, Kimmig R; Uterus Commission of the Gynecological Oncology Working Group  (AGO). J Cancer Res Clin Oncol. 2009 Oct;135(10):1387-91. Epub 2009 Apr 11.
  3. Fung-Kee-Fung M, Dodge J, Elit L, Lukka H, Chambers A, Oliver T, Gynecology Cancer Disease Site Group. Follow-up after primary therapy for endometrial cancer. Toronto (ON): Cancer Care Ontario (CCO); 2006 Jan 10. 26 p. (Evidence-based series; no. 4-9).

(Evidence level IV)

Search date: January 2010

Classification of evidence levels

Ia Evidence obtained from meta-analysis of randomised controlled trials.

Ib Evidence obtained from at least one randomised controlled trial.

IIa Evidence obtained from at least one well-designed controlled study without randomisation.

IIb Evidence obtained from at least one other type of well-designed quasi-experimental study.

III Evidence obtained from well-designed non-experimental descriptive studies, such as comparative studies, correlation studies and case studies.

IV Evidence obtained from expert committee reports or opinions and/or clinical experience of respected authorities.

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Date published: 18/01/2010

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