Fetal and Maternal Risks of Diethylstilboestrol Exposure in Pregnancy (RCOG Statement 2)

We do not plan to update this statement and it has been archived.

Advice to women exposed in utero to DES should have an initial colposcopic examination. In the absence of an abnormality at that first examination, only routine cervical screening is required.  Women whose initial examination showed an abnormality or stigmata of DES exposure may require annual colposcopic examination of the vagina and cervix, in specialist centres, possibly for life.  However, this should be considered on an individual basis by the woman concerned and her gynaecologist.

DES exposed women have now got to an age when breast cancer is common.  A number of studies have suggested such women are at an increased risk of breast cancer.  It is therefore particularly important that women in this situation take up their invitation to breast screening when it is offered and remain breast aware at all times. 

Please refer to the NHS National Cancer Screening Programmes website.

Date published: 01/04/2002

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