3.1.3 Base editing: Can we cure genetic disease by rewriting DNA?
Video 16min TED Talk
Chemical biologist David R. Liu, whose lab developed this breakthrough technology, provides an inspiring introduction to base editing. This takes the promise of CRISPR to the next level where individual bases can be altered bringing the promise of preventing or curing diseases caused by single gene mutations.
“Good format and highly engaging.”
“A good summary of the challenges of single base pair editing.”
3.1.4 Next Generation Sequencing (NGS)
Video 31min presentation
A detailed look at DNA sequencing explaining how modern DNA analysis is carried out. It covers Sanger sequencing, sequencing by synthesis (Illumina), nanopore sequencing (Oxford Nanopore), long read sequencing (Pacific Biosciences). This provides essential understanding for those in fetal medicine and preimplantation genetic testing, and cancer diagnosis and treatment.