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Obstetric Impact of Treatment for Cervical Intraepithelial Neoplasia (Scientific Impact Paper No. 21)

Published: 23/06/2010

This is the first edition of this Scientific Impact Paper.

In countries like the UK, where a cervical screening programme has been successfully applied, the incidence and mortality from cervical cancer has significantly decreased. However, the mean age of women identified as having cervical intraepithelial neoplasia (CIN) and requiring treatment is around 30 years, and it is now common for treatment to occur before women are starting their families.

Therefore, there is a need to consider local treatment for CIN. Treatment of CIN should not be compromised in terms of efficacy and should be as efficient as possible, but should not lead to long-term effects on future fertility and pregnancy outcome. Excisional techniques are usually performed under local anaesthesia in an outpatient setting and are easy to perform. However, there is increasing evidence that excisional procedures for treatment of CIN are associated with preterm delivery and might be associated with perinatal mortality.

This paper discusses the current evidence on obstetric complications following treatment for CIN.