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Botulinum Toxin for an Overactive Bladder (Scientific Impact Paper No. 42)

Published: 05/02/2014

This is the first edition of this Scientific Impact Paper.

Preparations of botulinum toxin (BoNT-A) have rapidly become established as a treatment option for detrusor overactivity (DO) and overactive bladder (OAB). Although data were initially limited, several randomised controlled trials have been published in the last 3 years. However, the role of BoNT-A in treatment algorithms is yet to be fully established.

This paper reviews the existing data and provides suggested guidance on initial dosing and the advice clinicians should give to patients, before highlighting where information is still lacking.